ISCRAM is a forum where researchers and practitioners from all around the world meet every year to share experiences and raise challenges in all the aspects related to the design, development, and use of information systems to improve the management of crisis and disaster situations. The 16th International Conference on Information Systems for Crisis Response and Management will be held in Valencia (Spain) from May 19 to 22, 2019, following successful previous editions celebrated in Brussels (2004 & 2005), Newark (2006), Delft (2007), Washington DC (2008), Gothenburg (2009), Seattle (2010), Lisbon (2011), Vancouver (2012), Baden-Baden (2013), State College (2014), Kristiansand (2015), Rio de Janeiro (2016), Albi (2017) and Rochester (2018).